Blood group phenotypes

An individual's phenotype is determined by the expression of antigens on their red cells. The frequency of blood group phenotypes within a population is determined by the ethnic diversity of a region due to the patterns of inheritence of the blood groups.
 

Major blood group phenotypes and their frequencies*

ISBT Number / System Name / [System Symbol]

Phenotype % Frequency
A1 29.7
A2 9.3
B 11.4
O 46.1
A1B 2.3
A2B 1.2
Phenotype % Frequency
MMSS 6
MMss 9.1
MMSs 14.4
MNSS 3
MNss 23.3
MNSs 22.7
NNSS 0.4
NNss 15.6
NNSs 5.5
Phenotype % Frequency
P1+ 74.8
P1 25.2
Phenotype % Frequency
See Rh phenotypes  
Phenotype % Frequency
Lu(a+b–) 0.2
Lu(a–b+) 92.3
Lu(a+b+) 7.5
Lu(a–b–) Rare
Phenotype % Frequency
K– k+ 90.9
K+ k– 0.4
K+ k+ 8.7
Kp(a+b–) <0.1
Kp(a–b+) 97.8
Kp(a+b+) 2.2
Phenotype % Frequency
Le(a+b–) 22.4
Le(a–b+) 72.3
Le(a–b–) 5.3
Phenotype % Frequency
Fy(a+b–) 19.7
Fy(a–b+) 32.7
Fy(a+b+) 47.6
Fy(a–b–) very rare
Phenotype % Frequency
Jk(a+b–) 26.3
Jk(a–b+) 23.6
Jk(a+b+) 50.1
Jk(a–b–) rare
Phenotype % Frequency
Di(a+b–) <0.01
Di(a-b+) >99.9
Di(a+b+) <0.1
Wr(a+) <0.01
Wr(b+) High incidence
Phenotype % Frequency
Yt(a+b–) 91.9
Yt(a–b+) 0.3
Yt(a+b+) 7.8
Phenotype % Frequency
Xg(a+) Male-65.6
  Female-88.7
Xg(a–) Male-34.4
  Female-11.3
Phenotype % Frequency
Sc:1,–2 99
Sc:–1,2 Rare
Sc:1,2 1
Sc:1,–2,Rd+ Rare
Sc:1,2,Rd+ Rare
Phenotype % Frequency
Do(a+b–) 18
Do(a–b+) 33
Do(a+b+) 49
Gy(a–) Rare
Phenotype % Frequency
Co(a+b–) 90
Co(a–b+) 0.5
Co(a+b+) 9.5
Phenotype % Frequency
LW(a+b–) 97
LW(a–b+) Rare
LW(a+b+) 3
Phenotype % Frequency
Chido phenotype  
CH/RG: 1,2,3 88.2
CH/RG: 1,–2,3 4.9
CH/RG: 1,2,–3 3.1
CH/RG: –1,–2,–3 3.8
CH/RG: –1,2,-3 Rare
CH/RG: 1,–2,–3 Rare
Rodgers phenotype  
CH/RG: 11,12 95
CH/RG: 11,–12 3
CH/RG: –11,–12 2
Phenotype % Frequency
H High incidence
Phenotype % Frequency
Kx High incidence
Phenotype % Frequency
Ge:2,3,4 >99.9
Ge:–2,3,4 (Yus type) Rare
Ge:–2,–3,4 (Gerbich type) Rare
Ge:–2,–3,–4 (Leach) Rare
Phenotype % Frequency
Cra, Tca, Dra, Esa High Incidence
Tcb, Tcc, WESa Low incidence
Phenotype % Frequency
Kn(a+b–) 94.5
Kn(a–b+) 1
Kn(a+b+) 4.5
McC(a+) 98
Sl(a+) 98
Yk(a+) 92
Phenotype % Frequency
In(a+b–) Rare
In(a–b+) 99.9
In(a+b+) <0.1
Phenotype % Frequency
Ok(a+) 100
Ok(a–) Rare
Phenotype % Frequency
MER2 92
Phenotype % Frequency
JMH High incidence
Phenotype % Frequency
I High incidence
Phenotype % Frequency
P High incidence
Phenotype % Frequency
GIL High incidence
Phenotype % Frequency
Duclos High incidence
Phenotype % Frequency
FORS1 Low incidence
Phenotype % Frequency
Jra High incidence
Phenotype % Frequency
Lan High incidence
Phenotype % Frequency
Vel High incidence
Phenotype % Frequency
CD59.1 High incidence
Phenotype % Frequency
AUG1  
AUG2 >99%
Phenotype % Frequency
KANNO1  
Phenotype % Frequency
Sd(a+) 90%
Sd(a-) 10%
Phenotype % Frequency
VER High incidence
RIF High incidence
Phenotype % Frequency
PEL High incidence
Phenotype % Frequency
MAM High incidence
Phenotype % Frequency
Emm High incidence
Phenotype % Frequency

Antigen Collections (series 200)**

Phenotype % Frequency
Csa 95%
Csb 34%
Phenotype % Frequency
I <1
Phenotype % Frequency
Era >99
Erb <1
Er3 >99

210

Phenotype % Frequency
Lec 1
Led 6
Phenotype % Frequency
HU  
M1  
Tm  
Can  
Sext  
Sj  

Low incidence antigens (700 series)**

Phenotype % Frequency
By, Chra, Bi, Bxa, Toa, Pta, Rea, Jea , Lia, Milne, RASM, JFV, Kg, JONES, HJK, HOFM, REIT <1

High incidence antigens (901 series)**

Phenotype % Frequency
AnWj, ABTI, LKE >90

Note:

*Unless indicated, frequencies are based on blood group statistics of Australian blood donors.

** Frequency typically based on data from Caucasian populations, however variations do exist for some phenotypes in different ethnic groups. 

 

References
  1. Cohn CS, Eder AF, Delaney M, Johnson ST, Katz LM, 2020, AABB Technical Manual 20th Edition.
  2. International Society of Blood Transfusion (ISBT). Red cell immonogenetics and blood group terminology. [cited 2020 June 26 ]. Available from: http://www.isbtweb.org/working-parties/red-cell-immunogenetics-and-blood-group-terminology.

  3. Reid ME, Lomas-Francis C, Olsson ML,2012, The Blood Group Antigen Facts Book 3rd Edition.