Cryodepleted plasma

07 LRI Cryodepleted plasma.pngThis component is the supernatant remaining after cryoprecipitate has been removed from fresh frozen plasma, which is either derived from whole blood or collected via apheresis.

It contains most clotting factors in similar amounts to fresh frozen plasma but is deficient in Factor VIII, fibrinogen, von Willebrand Factor (the high molecular weight multimers are more thoroughly removed than the smaller multimers), Factor XIII and fibronectin.

Cryodepleted plasma can be stored for 12 months at –25˚ C or below.

Typical unit content and specifications

The typical unit content data is derived from Lifeblood process control testing. For each parameter, the mean value (± 1 SD) and specification is shown.

Unless otherwise specified data is for the period 1 January to 31 December 2018.*

Volume (mL)
242 ± 13 (215265)
*Data from 3 December 2018 to 31 March 2019
Volume (mL)
755 ± 6 (495–605)



Cryodepleted plasma derived from whole blood and apheresis is available in all ABO groups.


There is no modification available for cryodepleted plasma.


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