Cryodepleted plasma

07 LRI Cryodepleted plasma.pngCryodepleted plasma is the supernatant plasma left after removal of cryoprecipitate from fresh frozen plasma.

It contains most clotting factors in similar amounts to fresh frozen plasma but is deficient in factor VIII, fibrinogen, von Willebrand factor (the high molecular weight multimers are more thoroughly removed than the smaller multimers), factor XIII and fibronectin.

Cryodepleted plasma has a shelf-life of 12 months when stored at –25˚ C or below.

Typical unit content and specifications

The typical unit content data is derived from Lifeblood process control testing. For each parameter, the mean value (± 1 SD) and specification is shown.

Unless otherwise specified data is for the period 1 January to 31 December 2020.*

Volume (mL)
241 ± 13 (215265)
Volume (mL)
752 ± 16 (765–825)



Cryodepleted plasma is available in all ABO groups. Matching for RhD type is not required.


There is no modification available for cryodepleted plasma. matching for RhD type is not required.


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