Cryoprecipitate is prepared from plasma derived from both whole blood and apheresis donations. Fresh frozen plasma is slowly thawed at a temperature between 1–6 ˚C and the resulting cold-insoluble precipitate is recovered and then refrozen.
One unit of apheresis cryoprecipitate is approximately equivalent to 2 units of whole blood cryoprecipitate.
Cryoprecipitate contains most of the factor VIII, fibrinogen, factor XIII, von Willebrand factor and fibronectin found in fresh frozen plasma.
Cryoprecipitate has a shelf-life of 12 months when stored at –25º C or below.
Typical unit content and specifications
The typical unit content data is derived from Lifeblood process control testing. For each parameter, the mean value (± 1 SD) and specification is shown.
Unless otherwise specified data is for the period 1 January to 31 December 2020.
Cryoprecipitate is available in all ABO groups. Matching for RhD group is not required.
There are no modifications available for cryoprecipitate.