Cryoprecipitate

07 LRI Cryoprecipitate.pngCryoprecipitate is prepared from plasma derived from both whole blood and apheresis donations. Fresh frozen plasma is slowly thawed at a temperature between 1–6 ˚C and the resulting cold-insoluble recovered and then refrozen.

One unit of apheresis cryoprecipitate is approximately equivalent to 2 units of whole blood cryoprecipitate.

Cryoprecipitate contains most of the factor VIII, fibrinogen, factor XIII, von Willebrand factor and fibronectin found in fresh frozen plasma.

Cryoprecipitate has a shelf-life of 12 months when stored at –25º C or below.

 

Typical unit content and specifications

The typical unit content data is derived from Lifeblood process control testing. For each parameter, the mean value (± 1 SD) and specification is shown.

Unless otherwise specified data is for the period 1 January to 31 December 2018.

Volume (mL)
36 ± 2 (3040)
Factor VIIIc (IU/unit)
151 ± 30 (> 70)
Fibrinogen (mg/unit)
357 ± 110 (> 140)
Von Willebrand factor (IU/unit)
294 ± 69 (> 100)
Volume (mL)
60 ± 2 (5466)
Factor VIIIc (IU/unit)
347 ± 57 (> 70)
Fibrinogen (mg/unit)
906 ± 268 (> 140)
Von Willebrand factor (IU/unit)
897 ± 152 (> 100)

 

Availability

Cryoprecipitate is available in all ABO groups. Matching for RhD group is not required.
 

Modifications

There are no modifications available for cryoprecipitate.

 

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