This component, either derived from whole blood or collected via apheresis, is prepared by thawing fresh frozen plasma between
1–6 ˚C and recovering the precipitate. The cold-insoluble precipitate is refrozen.
One unit of cryoprecipitate apheresis is approximately equivalent to 2 units of cryoprecipitate derived from whole blood.
It contains most of the Factor VIII, fibrinogen, Factor XIII, von Willebrand Factor and fibronectin from fresh frozen plasma.
Cryoprecipitate can be stored for 12 months at –25º C or below.
Typical unit content and specifications
Information is based on the typical unit content (mean ± 1 SD) from Blood Service data (1 January to 31 December 2016 inclusive) and acceptable specification limits (in parentheses).
Cryoprecipitate derived from whole blood and apheresis is available in all ABO groups.
There is no modification available for cryoprecipitate.