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Cryoprecipitate

Submitted by admin on Tue, 2010-03-02 10:49

07 LRI Cryoprecipitate.pngThis component, either derived from whole blood or collected via apheresis, is prepared by thawing fresh frozen plasma between
1–6 ˚C and recovering the precipitate. The cold-insoluble precipitate is refrozen.

One unit of cryoprecipitate apheresis is approximately equivalent to 2 units of cryoprecipitate derived from whole blood.

It contains most of the Factor VIII, fibrinogen, Factor XIII, von Willebrand Factor and fibronectin from fresh frozen plasma.

Cryoprecipitate can be stored for 12 months at –25º C or below.

 

Typical unit content and specifications

The typical unit content data is derived from Lifeblood process control testing. For each parameter, the mean value (± 1 SD) and specification is shown.

Unless otherwise specified data is for the period 1 January to 31 December 2018.

Cryoprecipitate Whole Blood

Volume (mL)
36 ± 2 (30–40)
Factor VIIIc (IU/unit)
151 ± 30 (> 70)
Fibrinogen (mg/unit)
357 ± 110 (> 140)
Von Willebrand factor (IU/unit)
294 ± 69 (> 100)

Cryoprecipitate Apheresis

Volume (mL)
60 ± 2 (54–66)
Factor VIIIc (IU/unit)
347 ± 57 (> 70)
Fibrinogen (mg/unit)
906 ± 268 (> 140)
Von Willebrand factor (IU/unit)
897 ± 152 (> 100)

 

Availability

Cryoprecipitate derived from whole blood and apheresis is available in all ABO groups.
 

Modifications

There is no modification available for cryoprecipitate.

 

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Updated on 14 February, 2020