Cryoprecipitate

07 LRI Cryoprecipitate.pngCryoprecipitate is prepared from plasma derived from both whole blood and apheresis donations. Fresh frozen plasma is slowly thawed at a temperature between 1–6 ˚C and the resulting cold-insoluble precipitate is recovered and then refrozen.

One unit of apheresis cryoprecipitate is approximately equivalent to 2 units of whole blood cryoprecipitate.

Cryoprecipitate contains most of the factor VIII, fibrinogen, factor XIII, von Willebrand factor and fibronectin found in fresh frozen plasma.

Cryoprecipitate has a shelf-life of 12 months when stored at –25º C or below.

 

Typical unit content and specifications

The typical unit content data is derived from Lifeblood process control testing. For each parameter, the mean value (± 1 SD) and specification is shown.

Unless otherwise specified data is for the period 1 January to 31 December 2020.

Volume (mL)
36 ± 2 (3040)
Factor VIIIc (IU/unit)
161 ± 33 (> 70)
Fibrinogen (mg/unit)
380 ± 114 (> 140)
Von Willebrand factor (IU/unit)
260 ± 51 (> 100)
Volume (mL)
60 ± 2 (5466)
Factor VIIIc (IU/unit)
436 ± 70 (> 70)
Fibrinogen (mg/unit)
1067 ± 308 (> 140)
Von Willebrand factor (IU/unit)
732 ± 151 (> 100)

 

Availability

Cryoprecipitate is available in all ABO groups. Matching for RhD group is not required.
 

Modifications

There are no modifications available for cryoprecipitate.

 

<< Previous page: Cryodepleted plasma  |  Next page: Whole blood >>