This modification is prepared by adding glycerol, a cryoprotective agent, to red cells before freezing. Frozen red cells may be stored for up to 10 years and for longer intervals if there is a particular need for specific units.
Remove the glycerol from thawed component prior to transfusion. This is done by washing the cells with sodium chloride. The washed red cells are then resuspended in additive solution.
When should I use this modification?
Use frozen red cells for red cells with unusual phenotypes and for autologous collections when liquid-preserved blood cannot fulfil demands.
These are for patients with rare red cell phenotypes or multiple red cell antibodies.