Washed components

Red cells are washed to remove the majority of unwanted plasma proteins, antibodies and electrolytes. 

There is some loss of red cells during processing.

When should I use this modification?

The following groups of patients should receive washed components:
  • patients with reactions to transfused plasma proteins (eg patients who have IgA deficiency and antibodies to IgA)
  • multi-transfused patients with severe recurrent febrile, urticarial and possible anaphylactic reactions
  • patients with paroxysmal nocturnal haemoglobinuria who experience reactions despite receiving group-specific leucocyte depleted fresh red cells
  • rarely, patients with T-activation when units from donors with low anti-T titres are not available
  • patients with severe autoimmune haemolytic anaemia where excess complement may worsen red cell destruction.